Make clear the main direction of scientific research and play a national chess game. In accordance with the arrangement of the Central Leading Group for COVID-19 Response, and under the joint prevention and control mechanism of The State Council,
the Ministry of Science and Technology, together with 12 departments including health, drug administration and education, set up a research task force and a group of 14 academicians,
and set up nine specialized groups for key work to pool the country's leading scientific research forces. Give full play to the advantages of multi-departmental coordination and cross-departmental joint operations,
strengthen central-local coordination, military-civilian coordination, and industry-university-research and application-oriented coordination, focus on the five key tasks of clinical treatment,
drug and vaccine research and development, detection technology and products, virus etiology and epidemiology, and animal model construction, and closely meet the urgent needs of first-line treatment in Wuhan, Hubei Province. Forty-seven emergency projects have been deployed to carry out scientific research on epidemic prevention and control.
Adhere to the combination of scientific research and clinical, prevention and control frontline, to provide strong scientific and technological support for "diagnosable, treatable,preventable, traceable". In terms of accessibility, nucleic acid test kits were developed at the beginning of the epidemic, which solved an urgent problem. In terms of treatability,
more than 5,000 drugs for SARS, MERS and common coronaviruses have been screened, and the most effective drugs have been selected for clinical trial. Clinical studies on chloroquine phosphate and Fapiravir have been carried out for the treatment of mild and ordinary patients,
and chloroquine phosphate has been included in the diagnosis and treatment plan and has become a clinical treatment drug. For severe (critical) patients, focus on the use of convalescent plasma, stem cell therapy and other relatively safe and effective means.
Traditional Chinese medicine and integrated treatment of traditional Chinese and western medicine have achieved remarkable results in blocking the development of mild patients to severe patients. In the past more than a month,
a number of drugs and treatment technologies have been continuously expanded in clinical treatment, which has played an important role in optimizing treatment plans and formulating treatment strategies for classification and stratification.
At present, the screening and clinical studies of a new batch of potentially effective drugs are being promoted. In terms of prevention, vaccine research and development should be carried out in parallel according to the five technical routes of inactivated vaccine,
viral recombinant protein vaccine, adenovirus vector vaccine, live attenuated influenza virus vector vaccine, and nucleic acid vaccine, and the working process should be optimized to the maximum extent under the premise of respecting scientific laws and ensuring safety and effectiveness,
and the research and review linkage should be ensured to ensure that the progress is not later than that of foreign countries. Research on multiple transmission routes should be carried out to provide a scientific basis for targeted prevention and control during the resumption of work and production.
New technologies such as artificial intelligence and big data will be used to predict the development trend of the epidemic and select prevention and control strategies. In terms of traceability,
efforts were made to identify the source of the virus from four aspects: environmental traceability, animal traceability, human traceability and molecular traceability.
At the same time, the construction of animal models will be accelerated to provide basic support for drug screening, vaccine research and development, and virus detection. Strengthen communication and exchanges with the World Health Organization and foreign research institutions, and actively carry out cooperative research.
In the "mobile emergency intelligent TCM pharmacy" of Wuhan Jiangxia Makeshift Hospital, the staff took down the medicine bottles containing the single flavor medicine contained in the prescription, scanned them one by one, and prepared to make medicine. Photo by Shen Bohan, Xinhua News Agency
We will strengthen standardized management and ensure that scientific research is carried out in an orderly manner. Strengthen the management of human genetic resources in drug development and clinical trials to ensure that scientific data and information are autonomous and controllable.
Improve the safety management of high-level pathogenic microbiology laboratories, and further enhance the awareness and ability of risk prevention and control of biosafety. Strengthen the standardized management of drug clinical research order in medical institutions,
and put forward clear requirements for orderly drug clinical research throughout the country during the launch of the public health emergency mechanism. We will establish a standardized mechanism for releasing information on scientific research results,
and strengthen public opinion guidance and expected management. We will guide researchers to devote themselves to tackling key tasks, write their papers on the front line of epidemic prevention and control,
uphold a scientific attitude, grasp the laws of scientific research, explore scientific methods, and strive to produce more practical and useful scientific research results.