2023 is the "outbreak year" of domestic innovative drugs, not only an unprecedented number, but also a milestone breakthrough from small molecular chemical drugs to macromolecular biological drugs. In the beginning of 2024,
Anrui Bio (the youngest small molecule biotechnology company to cooperate with MNC), Yilian Bio (the most authorized ADC company) and Bowang Pharmaceutical (the first Chinese company to cooperate with MNC in the field of small nucleic acid),
which were incubated by Xingze Capital, completed four BD transactions, and rode off the record. These three companies, together with Csinovi Pharmaceutical, which is also popular in BD, and Sanofi China, which is the representative of MNC,
have explored the space that can be tapped in China's BD platform. Policy support has played a key role in it. For example, in the past, the government has issued a large number of support policies in basic innovation, industrial innovation, scientific and technological innovation, etc., providing the cornerstone of innovative vitality for biomedicine-based medicine.
The biomedical industry cannot be separated from "long-term capital and patient capital". Wang Li, founder of Heyuan Medical Devices (Shanghai) Co., LTD., believes that patient capital is related to the characteristics of the fund.
As a company focusing on heart failure and committed to the research and development of global innovative products, it is very important to find investors who are consistent with the philosophy and direction of the company, so that both sides can have the opportunity to move forward in parallel, which is a process of mutual selection and understanding.
The biomedical industry is a recognized hard-core track, and China, as one of the most competitive players, is running on this track at full speed. As a strategic emerging industry related to the national economy,
people's livelihood and national security, market demand superimposed by multiple factors such as policy guidance, scientific and technological innovation, and capital assistance,
the development of China's biomedical industry will pass through the winter of capital and move towards the golden age.The 2024 Science and Technology Annual meeting of the Chinese Society of Environmental Sciences was held
The 2024 Science and Technology Annual Meeting of the Chinese Society of Environmental Sciences was held in Wuhan, Hubei province. The theme of this annual conference is "Scientific and Technological Innovation enables the construction of Beautiful China".
Minister of Ecology and Environment Huang Runqiu attended the meeting and delivered a keynote report. Deputy Secretary of CPC Hubei Provincial Committee and Governor Wang Zhonglin attended the meeting and delivered a speech.
Huang Runqiu made a keynote speech on the topic of "In-depth Learning from the Spirit of the National Conference on Ecological and Environmental Protection to Comprehensively Promote the construction of Beautiful China".
The present and future period is an important period for the construction of a beautiful China. We will support high-quality development with high-quality ecological environment, and comprehensively promote the modernization of harmonious coexistence between man and nature with the construction of beautiful China.
Scientific and technological progress will lead the coordinated progress of carbon reduction, pollution reduction, green expansion and growth, effectively promote the battle against pollution prevention and control, ecological environment protection and restoration,
and all-round green transformation of economic and social development, and comprehensively safeguard the construction of a beautiful China. Hubei Province is rich in ecological resources, vibrant innovation vitality,
and superior scientific and technological innovation environment, making it an ideal place for ecological environmental scientific and technological innovation. We will strengthen innovation-driven development,
promote synergies in reducing pollution and carbon emissions, promote green transformation in the industrial structure, energy structure, transport structure, and urban and rural development, and activate new engines of green and low-carbon development.
Create a first-class ecology, coordinate the coordinated development of education, science and technology, and talents in the field of ecological environment, build a good government guidance fund group,
enrich the fertile soil for innovation, build a green and low-carbon innovation choice, accelerate the construction of beautiful Hubei, and realize the green rise.
I hope to take this annual meeting as an opportunity to work hand in hand with the vast number of friends in the ecological environment and science and technology industry to pursue new and green, and jointly draw a new picture of the construction of beautiful China and create a new situation in the construction of beautiful China.
At the meeting, the "2023 Environmental Protection Science and Technology Award", the "Sixth Chinese Society of Environmental Science Young Scientist Award" and the "Chinese Society of Environmental Science 2024 Member" certificate were awarded.
Zhang Wentong, Vice governor of Hubei Province, and Cheng Yongwen, Deputy secretary of the CPC Central Committee and mayor of Wuhan, Hubei Province, attended the meeting.
Wang Jinnan, member of the Chinese Academy of Engineering, Member of the Standing Committee of the CPPCC National Committee, Deputy director of the Committee of Population, Resources and Environment and chairman of the Chinese Society of Environmental Sciences attended the meeting and delivered a speech. Liu Wenqing, He Kebin, Wang Yanxin, Ren Hongqiang and other academician experts attended the meeting.
Heads of relevant departments and subordinate units of the Ministry of Ecology and Environment, heads of some local ecological and environmental departments, representatives of scientific research institutes, institutions of higher learning, social organizations, enterprises and media attended the meeting.
The Annual Science and Technology Conference of the Chinese Society for Environmental Sciences is an academic exchange platform that serves the majority of ecological and environmental science and technology workers and promotes the innovation of ecological and environmental science and technology,
the transformation and application of achievements and the popularization of science and technology. The annual conference has set up keynote reports, special discussions and youth exchanges and other links, a total of 57 sub-venues, and released more than 700 academic reports.Chinese scientists reveal a new mechanism for plant regenerationProfessor Li Chuanyou's team from Shandong Agricultural University has made important achievements in the field of plant regeneration. The team found that REF1, a regenerative factor produced by cell injury, is an original injury signaling molecule that triggers tissue repair and organ regeneration. This discovery will bring significant application value to the field of plant gene research.
Cell damage is the primary physical inducement that triggers plants and animals to start the regeneration process. In the 1970s, scientists discovered that micropeptide signaling system and the plant hormone jasmonic acid regulate systemic defense responses in plants through a common signaling pathway.
In subsequent studies, the scientific community has a deep understanding of the signal transduction mechanism of plant systemic defense, but the mechanism of plant damage repair and organ regeneration is not well understood.
Professor Li Chuanyou's team has been studying tomato for a long time, using genetic means to analyze the plant systemic defense signaling pathway jointly regulated by systemins and jasmonic acid. After years of research, the team identified one of a series of tomato mutants with changes in systemin signaling pathways that showed deficits in both defense and regeneration.
In follow-up studies and comparative experiments on this mutant, the researchers identified the key role of a small peptide that was applied externally to significantly improve the tomato's regenerative capacity.
The team named it regeneration Factor REF1. Regeneration factor REF1 regulates the process of plant regeneration, including the recognition of receptor proteins, transcriptional activation of cell reprogramming regulatory factors, and further amplification of REF1 signals, etc., which have been confirmed by studies.
Using the regeneration factor REF1, the research team also found that in the plant kingdom, REF1 small peptides and their receptors are widely distributed in dicotyledon and monocotyledon plants. REF1 application can not only significantly improve the regeneration ability and genetic transformation efficiency of tomato,
but also increase the regeneration ability and genetic transformation efficiency of soybean, wheat and corn several times. This provides a convenient and universal solution to solve the bottleneck problem of low efficiency of crop genetic transformation in biological breeding.
