The new forms of future medicine represented by gene therapy, stem cells, digital therapy, and neural regulation in many areas of brain diseases have gradually shown specific "sunrise attributes".

It can be said that the next 10 years will be a golden age for the development of innovative drugs and innovative therapies for CNS diseases: most of the risk genes for CNS diseases may be discovered,

and the potential application of specific gene editing in non-human primate models will promote human understanding of brain disease mechanisms. More and more brain networks and neural circuits related to brain diseases and new targets regulating neural circuits will be discovered,

which is expected to inject new "stimulants" into the development of the medical industry while serving the traditional medical needs. For neurodegenerative diseases, the discovery of new markers from blood and new markers from cognitive characteristics,

as well as new discoveries of data-driven scientific laws, can help to type patients who are currently widely considered to be heterogeneous from the same disease, and thus provide new ways to accurately implement clinical treatment.

In recent years, brain science has made progress and breakthroughs in molecular cells, key components, software and hardware development, application systems, instruments and other aspects, and brain-computer interface has gradually entered the track of application.

In the short and medium term, due to the difficulty of invasive implantation technology, the risk of callus formation and immune reaction, and the long-term safety of implanted electrodes in gray matter is unknown, so the application of BCI in real clinical medicine still has certain challenges.

However, in the long term, brain-computer interface is one of the most important development directions and platform technologies in the field of brain science, which provides a key engineering interface for intervening in the brain,

and can carry the integration of future regulatory tools, measurement techniques, computational decoding methods, new electrode materials and brain-like chips. Once deployed at scale, the data provided by BCI will improve our understanding of the brain, ultimately facilitating the "integration" of man and machine.

The future industry of brain science may be distributed in seven fields

According to social and market demand, the future industry of brain science may focus on seven areas. That is, animal model of brain disease, gene and cell therapy of brain disease, intelligent technology of brain computer integration,

"killer" technology and resource sharing platform of brain science research, research and development of new drugs for brain disease, pro-community technology of brain function training and intervention, and management of adolescent brain intelligence development and emotional health based on brain cognitive law.

Take the research and development of new drugs for brain diseases as an example. Specifically, for major brain diseases such as stroke, Alzheimer's disease, Parkinson's disease, and brain aging,

the research and development of new drugs featuring small molecule and polypeptide drugs, as well as the development of brain disease drug screening technologies based on tissues and organoids.

Another example is the "killer" technology and resource sharing in brain science research, which is the world's first cutting-edge technology and equipment platform for brain atlas analysis of long-distance projection monkey brain atlas with cell precision, and open sharing of such "killer" technology and resources.

In June last year, Shenzhen issued the Opinions on the Development and Expansion of Strategic Emerging Industrial Clusters and the Cultivation and Development of future Industries, which will focus on the cultivation and development of eight future industries,

one of which is brain science and brain-like intelligence. At present, the rapid development of brain science research and talent gathering in Shenzhen, the industry has gathered nearly 100 brain science and brain-like intelligence and related upstream and downstream enterprises,

initially formed the future industrial agglomeration development trend, and with the full completion of all kinds of shared infrastructure, the development process of brain science and brain-like intelligence industry and the creation of new industrial ecology will also be greatly accelerated.

In the future, focusing on the major needs of technological innovation and industrial development in the strategic science and technology fields related to brain science and brain-like intelligence,

under the continuous improvement and guidance of national policies, increasing support for innovation subjects, research and development and industry incubation institutions and talent training in the field of brain science and brain-like intelligence will create a good ecological environment for the development of brain science industry in the future.

The development of brain science needs to seize the historic opportunity

The interdisciplinary, international and technology-leading characteristics of brain science and brain-like intelligence determine the cross-complementarity with other traditional industries and the catalytic effect on new business forms.