Red blood cell infusion is one of the most widely used cell therapy strategies in clinic. At present, red blood cells and other blood products mainly rely on volunteers to donate,

but there are problems such as insufficient donors, risk of infection, and lack of rare blood types. To obtain a large number of functional red blood cells through in vitro culture is a major way to solve the problem.

In order to achieve mass production of red blood cells in vitro, two key problems must be overcome: first, large-scale culture and expansion of erythroid progenitor cells; The second is to perform efficient terminal differentiation and generate functional enucleated red cells in vitro.

In the previous study, the team established a platform for enrichment, expansion and terminal differentiation of human erythroid progenitor cells, and initially achieved in vitro expansion of erythroid progenitor cells.

In this study, the team systematically explored and optimized the nutrients required for the terminal differentiation of red blood cells.

They found that physiological levels of metabolites and salt concentrations significantly enhanced erythroid progenitor cell proliferation and increased mature red blood cell production. Based on this, the researchers found that lipid metabolism plays an important role in the terminal differentiation of red blood cells,

and tried to use low density lipoprotein or cholesterol to completely replace human plasma and serum, successfully established a new chemical composition of the red blood cell induced differentiation system.

Liu Senquan said that compared with the traditional culture system, the serum-free red blood cell induced differentiation system is not only expected to greatly improve the production efficiency of red blood cells in vitro,

reduce production costs, but also effectively solve the problem of differences in the source and batch of plasma products. This breakthrough has laid a solid foundation for the large-scale,

efficient and standardized production of red blood cells in the future.The great man's hometown to realize the original heart of the revolutionary spirit passed on, the faculty of Engineering science party members into the great man's hometown

It is his "bathing place" all year round;

In the conference room of the First Normal College, the comrades collectively watched the red story educational films of Yang Kaihui, Ren Bishi and other predecessors. Liu Minghou, secretary of the Party Committee of the College,

taught a vivid Party lesson with the title of "Following the footsteps of the General Secretary and inheriting the Spirit of the older generation of revolutionaries".

He called on Party members to learn history and apply what they have learned, apply the fine work style of the older generation of revolutionaries to the actual teaching and scientific research work, adhere to moral education and cultivate people, and tell the Chinese story well.

Orange Island, the famous red education base, as one of the important places of the Chinese Revolution, has witnessed the glorious course of the Communist Party of China and the great struggle of the people.

The successful holding of the joint theme Party Day activities of "The Great Man's Hometown to realize the revolutionary spirit of the Torch" further strengthened the ideals and beliefs of Party members,

and also enhanced the cohesion of the grass-roots party organizations of the college. We are deeply aware of the responsibility and mission of college educators, and expressed the need to transform learning achievements into practical actions and pass on the revolutionary spirit.The School of Engineering Science held a kite festival

Spring flowers, kites fly. In order to carry forward the traditional culture of the Chinese nation, the "Spring Rili" kite Festival was successfully held. The event attracted many kite lovers to gather together for a spring kite appointment.

The staff provided a wealth of kite-painting tools at the activity site, and the students gave full play to their creativity and drew their own unique kite works. Some students playfully draw a lucky cat on the kite,

some students let angry birds leap onto the zheng, and some students draw the wish of "successful graduation and successful landing", hoping to let the kite fly into the sky with a good wish. After the kite was made, many students left their own marks on the wall of Spring Wish, leaving this common beauty.

West playground set up a number of small booths, each booth has a different game link, successfully completed the game can get a seal, you write I guess, Caterpillar battle, angry Birds, coin game and other game booths crowded.

The students demonstrated excellent creativity and teamwork spirit in the game. Slingshot, coins in the water, blindfolded cooperation, hunting for sandbags... The students excitedly shuttled between the booths, leaving a piece of laughter.